{"id":16170,"date":"2026-08-27T10:50:15","date_gmt":"2026-08-27T03:50:15","guid":{"rendered":"https:\/\/bvndgiadinh.org.vn\/?p=16170"},"modified":"2026-08-27T11:16:21","modified_gmt":"2026-08-27T04:16:21","slug":"phat-hien-khoi-u-nghi-ngo-ac-tinh-o-mat-nguoi-benh-duoc-dieu-tri-thanh-cong-bang-thuoc-nho-mat-khong-can-phau-thuat-tai-benh-vien-nhan-dan-gia-dinh-co-so-sai-gon","status":"publish","type":"post","link":"https:\/\/bvndgiadinh.org.vn\/?p=16170","title":{"rendered":"PH\u00c1T HI\u1ec6N KH\u1ed0I U NGHI NG\u1edc \u00c1C T\u00cdNH \u1ede M\u1eaeT: NG\u01af\u1edcI B\u1ec6NH \u0110\u01af\u1ee2C \u0110I\u1ec0U TR\u1eca TH\u00c0NH C\u00d4NG B\u1eb0NG THU\u1ed0C NH\u1ece M\u1eaeT, KH\u00d4NG C\u1ea6N PH\u1eaaU THU\u1eacT T\u1ea0I B\u1ec6NH VI\u1ec6N NH\u00c2N D\u00c2N GIA \u0110\u1ecaNH \u2013 C\u01a0 S\u1ede S\u00c0I G\u00d2N"},"content":{"rendered":"\n

M\u1ed9t n\u0103m c\u1ed9m x\u1ed1n, \u0111au r\u00e1t m\u1eaft, ng\u01b0\u1eddi \u0111\u00e0n \u00f4ng 48 tu\u1ed5i b\u1ea5t ng\u1edd ph\u00e1t hi\u1ec7n t\u1ed5n th\u01b0\u01a1ng b\u1ea5t th\u01b0\u1eddng \u1edf v\u00f9ng gi\u00e1c m\u1ea1c. Thay v\u00ec ph\u1eabu thu\u1eadt ngay, c\u00e1c b\u00e1c s\u0129 B\u1ec7nh vi\u1ec7n Nh\u00e2n d\u00e2n Gia \u0110\u1ecbnh C\u01a1 s\u1edf S\u00e0i G\u00f2n l\u1ef1a ch\u1ecdn m\u1ed9t h\u01b0\u1edbng \u0111i\u1ec1u tr\u1ecb b\u1eb1ng thu\u1ed1c nh\u1ecf m\u1eaft. Ch\u1ec9 sau m\u1ed9t chu k\u1ef3 \u0111i\u1ec1u tr\u1ecb, t\u1ed5n th\u01b0\u01a1ng \u0111\u00e3 thu nh\u1ecf r\u00f5 r\u1ec7t.<\/strong><\/p>\n\n\n\n

\"\"<\/figure>\n\n\n\n

M\u1ed8T N\u0102M CH\u1ecaU \u0110\u1ef0NG C\u1ea2M GI\u00c1C KH\u00d3 CH\u1ecaU \u1ede M\u1eaeT<\/strong><\/p>\n\n\n\n

Su\u1ed1t kho\u1ea3ng m\u1ed9t n\u0103m, anh L.V.T., 48 tu\u1ed5i, sinh s\u1ed1ng t\u1ea1i ph\u01b0\u1eddng T\u00e2n Thu\u1eadn, TP. H\u1ed3 Ch\u00ed Minh, th\u01b0\u1eddng xuy\u00ean c\u1ea3m th\u1ea5y m\u1eaft tr\u00e1i c\u1ed9m x\u1ed1n, \u0111au r\u00e1t nh\u01b0 c\u00f3 v\u1eadt g\u00ec \u0111\u00f3 trong m\u1eaft, g\u00e2y kh\u00f3 ch\u1ecbu trong sinh ho\u1ea1t h\u1eb1ng ng\u00e0y. V\u00ec ngh\u0129 ch\u1ec9 l\u00e0 v\u1ea5n \u0111\u1ec1 m\u1eaft th\u00f4ng th\u01b0\u1eddng n\u00ean tr\u01b0\u1edbc \u0111\u00f3 anh ch\u01b0a \u0111i kh\u00e1m v\u00e0 c\u0169ng ch\u01b0a \u0111i\u1ec1u tr\u1ecb.<\/p>\n\n\n\n

\u0110\u1ebfn khi c\u00e1c tri\u1ec7u ch\u1ee9ng k\u00e9o d\u00e0i, anh quy\u1ebft \u0111\u1ecbnh \u0111\u1ebfn Ph\u00f2ng kh\u00e1m M\u1eaft \u2013 B\u1ec7nh vi\u1ec7n Nh\u00e2n d\u00e2n Gia \u0110\u1ecbnh c\u01a1 s\u1edf S\u00e0i G\u00f2n. Qua th\u0103m kh\u00e1m, ThS.BSNT. Tr\u1ea7n C\u00f4ng Danh \u2013 b\u00e1c s\u0129 chuy\u00ean khoa M\u1eaft<\/strong> ph\u00e1t hi\u1ec7n t\u1ea1i v\u00f9ng r\u00eca gi\u00e1c m\u1ea1c m\u1eaft tr\u00e1i c\u1ee7a anh c\u00f3 m\u1ed9t kh\u1ed1i t\u1ed5n th\u01b0\u01a1ng b\u1ea5t th\u01b0\u1eddng h\u01a1i g\u1ed3, m\u00e0u tr\u1eafng x\u00e1m, b\u1ec1 m\u1eb7t b\u00f3ng, kh\u00f4ng \u0111\u1ec1u v\u00e0 c\u00f3 c\u00e1c m\u1ea1ch m\u00e1u n\u1ed5i r\u00f5 xung quanh.<\/p>\n\n\n\n

\u0110\u00e2y l\u00e0 nh\u1eefng d\u1ea5u hi\u1ec7u khi\u1ebfn b\u00e1c s\u0129 nghi ng\u1edd m\u1ed9t lo\u1ea1i t\u1ed5n th\u01b0\u01a1ng c\u00f3 t\u00ean l\u00e0 t\u00e2n s\u1ea3n t\u1ebf b\u00e0o v\u1ea3y b\u1ec1 m\u1eb7t nh\u00e3n c\u1ea7u<\/strong> (Ocular Surface Squamous Neoplasia – OSSN), m\u1ed9t t\u00ecnh tr\u1ea1ng c\u00e1c t\u1ebf b\u00e0o tr\u00ean b\u1ec1 m\u1eb7t k\u1ebft m\u1ea1c v\u00e0 gi\u00e1c m\u1ea1c t\u0103ng sinh b\u1ea5t th\u01b0\u1eddng, v\u1edbi m\u1ee9c \u0111\u1ed9 t\u1eeb t\u1ed5n th\u01b0\u01a1ng ti\u1ec1n ung th\u01b0 \u0111\u1ebfn ung th\u01b0 x\u00e2m l\u1ea5n<\/strong>. \u0110\u00e2y l\u00e0 m\u1ed9t trong nh\u1eefng kh\u1ed1i u \u00e1c t\u00ednh th\u01b0\u1eddng g\u1eb7p nh\u1ea5t \u1edf b\u1ec1 m\u1eb7t nh\u00e3n c\u1ea7u. Ph\u00e1t hi\u1ec7n v\u00e0 \u0111i\u1ec1u tr\u1ecb s\u1edbm gi\u00fap b\u1ea3o t\u1ed3n th\u1ecb l\u1ef1c, h\u1ea1n ch\u1ebf t\u00e1i ph\u00e1t v\u00e0 ng\u0103n t\u1ed5n th\u01b0\u01a1ng ti\u1ebfn tri\u1ec3n, x\u00e2m l\u1ea5n v\u00e0o c\u00e1c m\u00f4 xung quanh.<\/p>\n\n\n\n

\"\"<\/figure>\n\n\n\n

KH\u00d4NG PH\u1ea2I C\u1ee8 C\u00d3 T\u1ed4N TH\u01af\u01a0NG \u1ede M\u1eaeT L\u00c0 PH\u1ea2I PH\u1eaaU THU\u1eacT<\/strong><\/p>\n\n\n\n

Khi ph\u00e1t hi\u1ec7n m\u1ed9t t\u1ed5n th\u01b0\u01a1ng b\u1ea5t th\u01b0\u1eddng \u1edf b\u1ec1 m\u1eb7t nh\u00e3n c\u1ea7u, nhi\u1ec1u ng\u01b0\u1eddi th\u01b0\u1eddng ngh\u0129 ngay \u0111\u1ebfn ph\u1eabu thu\u1eadt. Tuy nhi\u00ean, t\u00f9y v\u00e0o \u0111\u1eb7c \u0111i\u1ec3m v\u00e0 m\u1ee9c \u0111\u1ed9 t\u1ed5n th\u01b0\u01a1ng, b\u00e1c s\u0129 c\u00f3 th\u1ec3 l\u1ef1a ch\u1ecdn ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb ph\u00f9 h\u1ee3p m\u00e0 kh\u00f4ng nh\u1ea5t thi\u1ebft ph\u1ea3i ph\u1eabu thu\u1eadt ngay.<\/p>\n\n\n\n

Sau khi \u0111\u00e1nh gi\u00e1 t\u00ecnh tr\u1ea1ng t\u1ed5n th\u01b0\u01a1ng, b\u00e1c s\u0129 ch\u1ec9 \u0111\u1ecbnh cho anh \u0111i\u1ec1u tr\u1ecb b\u1eb1ng thu\u1ed1c nh\u1ecf m\u1eaft 5-FU 1%<\/strong>. \u0110\u00e2y l\u00e0 dung d\u1ecbch \u0111\u01b0\u1ee3c pha ch\u1ebf theo quy tr\u00ecnh v\u00f4 khu\u1ea9n t\u1eeb thu\u1ed1c 5-fluorouracil v\u00e0 dung d\u1ecbch natri clorid 0,9%, sau \u0111\u00f3, Anh T. \u0111\u01b0\u1ee3c h\u01b0\u1edbng d\u1eabn nh\u1ecf thu\u1ed1c v\u00e0o m\u1eaft tr\u00e1i 4 l\u1ea7n m\u1ed7i ng\u00e0y trong v\u00f2ng 7 ng\u00e0y, sau \u0111\u00f3 ngh\u1ec9 3 tu\u1ea7n. \u0110\u00e2y \u0111\u01b0\u1ee3c xem l\u00e0 m\u1ed9t chu k\u1ef3 \u0111i\u1ec1u tr\u1ecb.<\/p>\n\n\n\n

\u0110i\u1ec1u \u0111\u00e1ng m\u1eebng l\u00e0 ngay sau chu k\u1ef3 \u0111\u1ea7u ti\u00ean, t\u00ecnh tr\u1ea1ng m\u1eaft c\u1ee7a anh \u0111\u00e3 c\u00f3 nh\u1eefng chuy\u1ec3n bi\u1ebfn r\u00f5 r\u1ec7t. T\u1ed5n th\u01b0\u01a1ng thu nh\u1ecf \u0111\u00e1ng k\u1ec3, b\u1ec1 m\u1eb7t kh\u1ed1i tr\u1edf n\u00ean ph\u1eb3ng h\u01a1n, c\u00e1c m\u1ea1ch m\u00e1u t\u0103ng sinh gi\u1ea3m \u0111i. C\u00f9ng v\u1edbi \u0111\u00f3, c\u1ea3m gi\u00e1c c\u1ed9m x\u1ed1n v\u00e0 \u0111au r\u00e1t c\u0169ng gi\u1ea3m \u0111\u00e1ng k\u1ec3, gi\u00fap anh d\u1ec5 ch\u1ecbu h\u01a1n trong sinh ho\u1ea1t h\u1eb1ng ng\u00e0y.<\/p>\n\n\n\n

Trong nh\u1eefng n\u0103m g\u1ea7n \u0111\u00e2y, tr\u00ean th\u1ebf gi\u1edbi xu h\u01b0\u1edbng \u0111i\u1ec1u tr\u1ecb<\/strong> OSSN<\/strong> \u0111\u00e3 chuy\u1ec3n t\u1eeb ph\u1eabu thu\u1eadt \u0111\u01a1n thu\u1ea7n sang \u01b0u ti\u00ean \u0111i\u1ec1u tr\u1ecb n\u1ed9i khoa b\u1eb1ng h\u00f3a tr\u1ecb t\u1ea1i ch\u1ed7<\/strong> \u1edf c\u00e1c tr\u01b0\u1eddng h\u1ee3p ph\u00f9 h\u1ee3p. Trong s\u1ed1 c\u00e1c thu\u1ed1c h\u00f3a tr\u1ecb t\u1ea1i ch\u1ed7, 5-fluorouracil (5-FU) 1% \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng r\u1ed9ng r\u00e3i nh\u1edd hi\u1ec7u qu\u1ea3 cao, chi ph\u00ed h\u1ee3p l\u00fd v\u00e0 mang t\u00ednh an to\u00e0n. [1][2]<\/p>\n\n\n\n

\"\"<\/figure>\n\n\n\n

\u0110\u1eeaNG XEM NH\u1eb8 NH\u1eeeNG KH\u00d3 CH\u1ecaU K\u00c9O D\u00c0I \u1ede M\u1eaeT<\/strong><\/p>\n\n\n\n

T\u1ed5n th\u01b0\u01a1ng b\u1ec1 m\u1eb7t nh\u00e3n c\u1ea7u c\u00f3 th\u1ec3 ban \u0111\u1ea7u ch\u1ec9 g\u00e2y nh\u1eefng tri\u1ec7u ch\u1ee9ng kh\u00e1 quen thu\u1ed9c nh\u01b0 c\u1ed9m m\u1eaft, \u0111\u1ecf m\u1eaft, c\u1ea3m gi\u00e1c c\u00f3 d\u1ecb v\u1eadt, ch\u1ea3y n\u01b0\u1edbc m\u1eaft ho\u1eb7c \u0111au r\u00e1t.<\/p>\n\n\n\n

Ch\u00ednh v\u00ec nh\u1eefng bi\u1ec3u hi\u1ec7n n\u00e0y d\u1ec5 b\u1ecb nh\u1ea7m v\u1edbi vi\u00eam k\u1ebft m\u1ea1c, kh\u00f4 m\u1eaft ho\u1eb7c m\u1ed9t k\u00edch \u1ee9ng th\u00f4ng th\u01b0\u1eddng n\u00ean nhi\u1ec1u ng\u01b0\u1eddi c\u00f3 xu h\u01b0\u1edbng t\u1ef1 theo d\u00f5i ho\u1eb7c tr\u00ec ho\u00e3n vi\u1ec7c \u0111i kh\u00e1m.<\/p>\n\n\n\n

Tr\u01b0\u1eddng h\u1ee3p c\u1ee7a anh T. l\u00e0 m\u1ed9t l\u1eddi nh\u1eafc r\u1eb1ng nh\u1eefng tri\u1ec7u ch\u1ee9ng k\u00e9o d\u00e0i \u1edf m\u1eaft kh\u00f4ng n\u00ean b\u1ecb b\u1ecf qua. Th\u0103m kh\u00e1m s\u1edbm gi\u00fap b\u00e1c s\u0129 x\u00e1c \u0111\u1ecbnh \u0111\u00fang nguy\u00ean nh\u00e2n, \u0111\u00e1nh gi\u00e1 m\u1ee9c \u0111\u1ed9 t\u1ed5n th\u01b0\u01a1ng v\u00e0 l\u1ef1a ch\u1ecdn h\u01b0\u1edbng \u0111i\u1ec1u tr\u1ecb ph\u00f9 h\u1ee3p.<\/p>\n\n\n\n

V\u1edbi OSSN, t\u00f9y t\u1eebng tr\u01b0\u1eddng h\u1ee3p, b\u00e1c s\u0129 c\u00f3 th\u1ec3 c\u00e2n nh\u1eafc c\u00e1c ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb kh\u00e1c nhau. Dung d\u1ecbch 5-FU 1% l\u00e0 m\u1ed9t trong nh\u1eefng l\u1ef1a ch\u1ecdn \u0111i\u1ec1u tr\u1ecb t\u1ea1i ch\u1ed7 ph\u00f9 h\u1ee3p, gi\u00fap h\u1ea1n ch\u1ebf nhu c\u1ea7u can thi\u1ec7p ph\u1eabu thu\u1eadt.<\/p>\n\n\n\n

T\u00edn hi\u1ec7u \u0111\u00e1p \u1ee9ng t\u00edch c\u1ef1c ngay sau chu k\u1ef3 \u0111\u1ea7u ti\u00ean c\u1ee7a anh T. cho th\u1ea5y vi\u1ec7c ph\u00e1t hi\u1ec7n v\u00e0 \u0111i\u1ec1u tr\u1ecb \u0111\u00fang h\u01b0\u1edbng c\u00f3 th\u1ec3 mang l\u1ea1i k\u1ebft qu\u1ea3 \u0111\u00e1ng kh\u00edch l\u1ec7, \u0111\u1ed3ng th\u1eddi g\u00f3p ph\u1ea7n b\u1ea3o t\u1ed3n b\u1ec1 m\u1eb7t nh\u00e3n c\u1ea7u.<\/p>\n\n\n\n

Th\u0103m kh\u00e1m s\u1edbm gi\u00fap ph\u00e1t hi\u1ec7n \u0111\u00fang nguy\u00ean nh\u00e2n v\u00e0 l\u1ef1a ch\u1ecdn ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb ph\u00f9 h\u1ee3p tr\u01b0\u1edbc khi t\u1ed5n th\u01b0\u01a1ng ti\u1ebfn tri\u1ec3n.<\/p>\n\n\n\n

L\u01b0u \u00fd: 5-FU 1% l\u00e0 thu\u1ed1c \u0111i\u1ec1u tr\u1ecb chuy\u00ean khoa, ph\u1ea3i \u0111\u01b0\u1ee3c pha ch\u1ebf \u0111\u00fang quy tr\u00ecnh, s\u1eed d\u1ee5ng theo \u0111\u01a1n v\u00e0 theo d\u00f5i b\u1edfi b\u00e1c s\u0129. Ng\u01b0\u1eddi b\u1ec7nh kh\u00f4ng t\u1ef1 mua, t\u1ef1 pha ho\u1eb7c t\u1ef1 \u00fd s\u1eed d\u1ee5ng.<\/strong><\/em><\/p>\n\n\n\n

PH\u00d2NG KH\u00c1M M\u1eaeT – B\u1ec6NH VI\u1ec6N NH\u00c2N D\u00c2N GIA \u0110\u1ecaNH C\u01a0 S\u1ede S\u00c0I G\u00d2N<\/strong><\/p>\n\n\n\n

\ud83d\udccd 125 L\u00ea L\u1ee3i, ph\u01b0\u1eddng B\u1ebfn Th\u00e0nh, TP.HCM<\/p>\n\n\n\n

T\u00e0i li\u1ec7u tham kh\u1ea3o:<\/strong><\/p>\n\n\n\n

    \n
  1. Bakal K et al. Efficacy of topical 5-Fluorouracil in the management of ocular surface squamous neoplasia: a study of 101 eyes. Int Ophthalmol. 2024;44:251.<\/li>\n\n\n\n
  2. Lan X, Zhang D, Luo S, et al. Topical 5-fluorouracil 1% versus surgical removal as a primary treatment modality for ocular surface squamous neoplasia: a comparison of recurrences and side effects. BMC Ophthalmology. 2025;25:600.<\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"

    M\u1ed9t n\u0103m c\u1ed9m x\u1ed1n, \u0111au r\u00e1t m\u1eaft, ng\u01b0\u1eddi \u0111\u00e0n \u00f4ng 48 tu\u1ed5i b\u1ea5t ng\u1edd ph\u00e1t hi\u1ec7n t\u1ed5n th\u01b0\u01a1ng b\u1ea5t th\u01b0\u1eddng \u1edf v\u00f9ng gi\u00e1c m\u1ea1c. Thay v\u00ec ph\u1eabu thu\u1eadt ngay, c\u00e1c b\u00e1c s\u0129 B\u1ec7nh vi\u1ec7n Nh\u00e2n d\u00e2n Gia \u0110\u1ecbnh C\u01a1 s\u1edf S\u00e0i G\u00f2n l\u1ef1a ch\u1ecdn m\u1ed9t h\u01b0\u1edbng \u0111i\u1ec1u tr\u1ecb b\u1eb1ng thu\u1ed1c nh\u1ecf m\u1eaft. Ch\u1ec9 sau m\u1ed9t […]<\/p>\n","protected":false},"author":5,"featured_media":16171,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_regular_price":[],"currency_symbol":[],"inline_featured_image":false,"_uag_custom_page_level_css":"","_monsterinsights_skip_tracking":false,"footnotes":"","_members_access_role":[],"_members_access_error":""},"categories":[255,56],"tags":[],"class_list":["post-16170","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-co-so-2","category-tin-tuc"],"aioseo_notices":[],"aioseo_head":"\n\t\t\n\t\n\t\n\t\n\t\n\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t